Most (if not all) 2TB USB Flash drives are fakes. They are only 64GB (or so) and usually contain bad memory chips anyway.
It is sometimes possible to boot Linux ISOs whether CSM or UEFI.
You will need to construct your own grub menu file (using F6 option in Ventoy). It depends on the distro.
If the kernel file will load under both legacy and UEFI64, then you can use the linux and initrd commands of grub2 to load them.
The problem is each ISO will require a bespoke grub2 menu.
Here is an example
https://rmprepusb.blogspot.com/2021/02/h...ivecd.html
It is sometimes possible to boot Linux ISOs whether CSM or UEFI.
You will need to construct your own grub menu file (using F6 option in Ventoy). It depends on the distro.
If the kernel file will load under both legacy and UEFI64, then you can use the linux and initrd commands of grub2 to load them.
The problem is each ISO will require a bespoke grub2 menu.
Here is an example
https://rmprepusb.blogspot.com/2021/02/h...ivecd.html