WinPE10 8 Sergei Strelec x86_x64 2021.01.05 EN.iso with Ventoy 1.0.70 UEFI64 on Lenovo IdeaPad 300 works for me.
If I go to Explorer, I can see a 'DVD Drive ( J: ) USB_STRELEC' virtual drive which shows that the ISO has been mounted as drive J: and many program shortcuts point to programs on J:.
If I go to Explorer, I can see a 'DVD Drive ( J: ) USB_STRELEC' virtual drive which shows that the ISO has been mounted as drive J: and many program shortcuts point to programs on J:.